Quote from persis.manu@gmail.com on October 9, 2025, 5:46 pmPreparation and Evaluation of Paracetamol Jelly
DR.A.M.Manoranjani, Shaik Zainab, Saadika Mehraj
Although syrups are commonly used dosage forms in children, patient non-compliance is a challenge that is meant to be addressed. In this regard, a jelly formulation was pondered which possesses enhanced aesthetic properties and is believed to rule out patient non-compliance i the pediatric population. The jelly formulation is prepared by the incorporation of a gelling agent. The commonly used gelling agent is gelatin, is employed in the preparation of jelly formulation. Varied concentrations of gelatin were studied. The jellies were prepared by the heating congealing method and evaluated for the characteristics, syneresis, weight variation, texture, appearance, FTIR studies and dissolution studies.
During the study, it was observed that lower concentrations of jellies showed fluidity whereas higher concentrations yielded stiffer jellies. Incorporation of pectin formed a softer consistency. The optimised jelly formulation showed appropriate consistency and complied with weight variation and content uniformity tests. The FTIR studies indicated drug excipient compatibility and drug stability during the preparation. The pH of the jellies was reported between 4.0-5.0
Preparation and Evaluation of Paracetamol Jelly
DR.A.M.Manoranjani, Shaik Zainab, Saadika Mehraj
Although syrups are commonly used dosage forms in children, patient non-compliance is a challenge that is meant to be addressed. In this regard, a jelly formulation was pondered which possesses enhanced aesthetic properties and is believed to rule out patient non-compliance i the pediatric population. The jelly formulation is prepared by the incorporation of a gelling agent. The commonly used gelling agent is gelatin, is employed in the preparation of jelly formulation. Varied concentrations of gelatin were studied. The jellies were prepared by the heating congealing method and evaluated for the characteristics, syneresis, weight variation, texture, appearance, FTIR studies and dissolution studies.
During the study, it was observed that lower concentrations of jellies showed fluidity whereas higher concentrations yielded stiffer jellies. Incorporation of pectin formed a softer consistency. The optimised jelly formulation showed appropriate consistency and complied with weight variation and content uniformity tests. The FTIR studies indicated drug excipient compatibility and drug stability during the preparation. The pH of the jellies was reported between 4.0-5.0
